SCHEMBL1471223

SCHEMBL1471223

[c]1nc(C2NCc3ccccc32)c[nH]1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 6/20 0.37
DRD2 P14416 4/20 0.37
DRD4 P21917 4/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
DRD5 P21918 1/20 0.37
DRD3 P35462 1/20 0.37
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
RECQL P46063 1/20 0.33
PRCP P42785 1/20 0.33
CYP2D6 P10635 3/20 0.33
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
TP53 P04637 2/20 0.32
CYP1A2 P05177 2/20 0.32
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11187934 0.74 ADRA1A (0.48) ADRA2ACYP2D6MEN1KMT2AALDH1A1
SCHEMBL6659680 0.71 TRPM5 (0.41) DRD1DRD2DRD4ADRA2AADRA2B
SCHEMBL18686402 0.71 DRD1 (0.35) DRD1DRD2DRD4ADRA2AADRA2B
SCHEMBL27741885 0.69 DRD1 (0.38) DRD1DRD2DRD4ADRA2AADRA2B
SCHEMBL6985456 0.67 PRCP (0.66) DRD1DRD2RECQLPRCPCYP2D6
SCHEMBL627815 0.66 PRCP (0.49) CHRNB2CHRNA4RECQLPRCPCYP2D6
SCHEMBL23356541 0.66 RECQL (0.35) DRD1DRD2DRD4ADRA2AADRA2B
SCHEMBL14494409 0.66 RAB9A (0.42) CYP2D6CYP3A4MEN1KMT2AGAA
SCHEMBL10516405 0.65 CYP2D6 (0.41) DRD1DRD2DRD4CHRNB2CHRNA4
SCHEMBL31444391 0.65 CHRNB2 (0.44) CHRNB2CHRNA4RECQLPRCPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9044413-B2 Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants SOLVAY USA INC. (US) 2015-06-02 US disclosed
US-8907033-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants SOLVAY USA INC. (US) 2014-12-09 US disclosed
EP-1322684-B1 PROCESSES TO CONTROL THE RESIDUAL MONOMER LEVEL OF COPOLYMERS OF TERTIARY AMINO MONOMER WITH A VINYL-FUNCTIONAL MONOMER SOLVAY USA INC (US) 2014-05-07 EP disclosed
US-20140034076-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2014-02-06 US disclosed
US-8580905-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2013-11-12 US disclosed
US-20130295032-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS RHODIA (US) 2013-11-07 US disclosed
US-20130237471-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2013-09-12 US disclosed
US-8492481-B2 Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants RHODIA INC. (US) 2013-07-23 US disclosed
US-8445616-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2013-05-21 US disclosed
US-20120208701-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2012-08-16 US disclosed
WO-2000071652-A2 DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS VOLUME AND SUDS DURATION ENHANCERS THE PROCTER & GAMBLE COMPANY (US) 2000-11-30 WO disclosed
WO-2000071660-A1 LIQUID DETERGENT COMPOSITIONS COMPRISING BLOCK POLYMERIC SUDS ENHANCERS THE PROCTER & GAMBLE COMPANY (US) 2000-11-30 WO disclosed
WO-2000071241-A1 COMPOSITIONS AND METHODS FOR USING POLYMERIC SUDS ENHANCERS THE PROCTER & GAMBLE COMPANY (US) 2000-11-30 WO disclosed
EP-1032634-A1 DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2000-09-06 EP disclosed
EP-1032633-A1 LIQUID DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS THE PROCTER & GAMBLE COMPANY (US) 2000-09-06 EP disclosed
WO-2000029535-A1 CLEANING PRODUCT WHICH USES SONIC OR ULTRASONIC WAVES THE PROCTER & GAMBLE COMPANY (US) 2000-05-25 WO disclosed
WO-2000029540-A1 ULTRASONIC CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-05-25 WO disclosed
WO-2000028874-A2 ULTRASONIC CLEANING DEVICE THE PROCTER & GAMBLE COMPANY (US) 2000-05-25 WO disclosed
WO-1999027057-A1 LIQUID DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS THE PROCTER & GAMBLE COMPANY (US) 1999-06-03 WO disclosed
WO-1999027058-A1 DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 1999-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208701-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS DSG1, DSTN, TES DRD1 1024/4885DRD2 1020/4885DRD4 699/4885
US-20130295032-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS CUTA, DAGLB, GZMB DRD1 1816/4885DRD2 1664/4885DRD4 1569/4885
US-20140034076-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS DSG1, DSTN, CUTA DRD1 929/4885DRD2 964/4885DRD4 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.