SCHEMBL5269864

SCHEMBL5269864

CCc1ccc2cccc(C(=O)NC3CN4CCC3CC4)c2n1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 7/20 0.62
KCNH2 Q12809 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5264415 0.92 HTR3A (0.61) HTR3AKCNH2
SCHEMBL5268531 0.86 HTR3A (0.61) HTR3AKCNH2
SCHEMBL5268069 0.85 HTR3A (0.58) HTR3AKCNH2
SCHEMBL5267272 0.81 HTR3A (0.63) HTR3AKCNH2
SCHEMBL5270359 0.81 HTR3A (0.63) HTR3AKCNH2
SCHEMBL5266545 0.81 HTR3A (0.58) HTR3AKCNH2
SCHEMBL7447481 0.78 HTR3A (0.56) HTR3A
SCHEMBL7447489 0.78 HTR3A (0.56) HTR3A
SCHEMBL1459350 0.77 CHRNA7 (0.67) HTR3A
SCHEMBL1006367 0.77 HTR3A (1.00) HTR3AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448530-B1 HETEROARYL CARBOXYLIC ACID AMIDES BAYER HEALTHCARE AG (DE) 2007-10-03 EP disclosed