Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266242 | 1.00 | LMNA (0.44) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL5267416 | 0.93 | ABCC4 (0.43) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL5266311 | 0.93 | ABCC4 (0.43) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL5264285 | 0.89 | ABCC4 (0.40) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL5264417 | 0.89 | ABCC4 (0.40) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL7100301 | 0.84 | ABCC1 (0.47) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL8623796 | 0.80 | LMNA (0.67) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL7098854 | 0.78 | ABCC4 (0.55) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL7099192 | 0.77 | ABCC4 (0.53) | LMNAHSD17B10ABCC4ABCC1ESR1 | |
| SCHEMBL6871662 | 0.76 | STS (0.69) | LMNAHSD17B10ABCC4ABCC1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418921-B1 | ANTI-TUMOUR 2-ALKOXYESTRADIOL SULFAMATES | STERIX LTD (GB) | 2007-10-03 | — | — | EP | claimed |
| EP-1418921-B1 | ANTI-TUMOUR 2-ALKOXYESTRADIOL SULFAMATES | STERIX LTD (GB) | 2007-10-03 | — | — | EP | disclosed |