Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 3/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.55 |
| ▸ | STS | P08842 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099192 | 0.90 | ABCC4 (0.53) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL6871662 | 0.89 | STS (0.69) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL8623796 | 0.87 | LMNA (0.67) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL7148062 | 0.87 | ABCC4 (0.55) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL4382857 | 0.83 | ABCC4 (0.80) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL6364570 | 0.83 | ABCC4 (0.80) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL7139122 | 0.83 | ABCC4 (0.51) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL7100301 | 0.82 | ABCC1 (0.47) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL5675177 | 0.81 | ESR1 (0.64) | STSLMNAHSD17B10ESR1SMN1; SMN2 | |
| SCHEMBL7147482 | 0.81 | ESR1 (0.64) | STSLMNAHSD17B10ESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775156-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ESTRA-1,3,5(10)-TRIENE DERIVATIVES | JENAPHARM GMBH (DE) | 2003-09-03 | — | — | EP | claimed |