Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270764 | 0.87 | KMT2A (0.52) | GPR27KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5269789 | 0.86 | MEN1 (0.51) | PGRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5267179 | 0.85 | KMT2A (0.50) | GPR27KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5268282 | 0.84 | TDP1 (0.54) | GPR27PGRKMT2AMEN1ALDH1A1 | |
| SCHEMBL5268976 | 0.84 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5269774 | 0.84 | KDM4E (0.55) | GPR27KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5268210 | 0.84 | SMN1; SMN2 (0.54) | GPR27KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5270621 | 0.84 | GPR27 (0.51) | GPR27KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5271604 | 0.84 | MEN1 (0.55) | GPR27KMT2AMEN1ALDH1A1 | |
| SCHEMBL5268920 | 0.84 | KCNA5 (0.47) | KMT2AMEN1ALDH1A1LMNAGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |