Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269255 | 0.90 | RAB9A (0.51) | SLC16A3MCL1BCL2A1BCL2BCL2L1 | |
| SCHEMBL5268485 | 0.88 | KCNA5 (0.51) | KCNA5MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5269046 | 0.86 | KCNA5 (0.50) | KCNA5MCL1BCL2A1MEN1KMT2A | |
| SCHEMBL5271844 | 0.85 | ALDH1A1 (0.52) | KCNA5KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL5269276 | 0.85 | ALDH1A1 (0.53) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5266472 | 0.85 | ALDH1A1 (0.53) | KCNA5SLC16A3KEAP1NFE2L2MEN1 | |
| SCHEMBL5268598 | 0.85 | KCNA5 (0.63) | KCNA5MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5267563 | 0.85 | KCNA5 (0.49) | KCNA5MCL1BCL2A1BCL2BCL2L1 | |
| SCHEMBL5270827 | 0.85 | KMT2A (0.58) | KCNA5KEAP1NFE2L2POLBMEN1 | |
| SCHEMBL5272580 | 0.84 | ALOX15 (0.49) | KCNA5MCL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |