Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269789 | 0.89 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5265268 | 0.86 | KCNA5 (0.46) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5266801 | 0.84 | GPR27 (0.54) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5272349 | 0.84 | MEN1 (0.47) | MEN1KMT2AGAAMAPTPGAM1 | |
| SCHEMBL5268522 | 0.83 | LMNA (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5269927 | 0.83 | LMNA (0.49) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5271810 | 0.82 | KCNA5 (0.50) | ALDH1A1LMNAGAASMN1; SMN2TDP1 | |
| SCHEMBL5268920 | 0.82 | KCNA5 (0.47) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL5268738 | 0.81 | METAP2 (0.44) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5273212 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |