Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576276 | 0.91 | LMNA (0.52) | LMNAALDH1A1GAASGMS2ABCB1 | |
| SCHEMBL2572231 | 0.87 | FFAR1 (0.48) | LMNAALDH1A1GAASGMS2ABCB1 | |
| SCHEMBL8064458 | 0.81 | ABCB1 (0.53) | LMNAALDH1A1GAASGMS2ABCB1 | |
| SCHEMBL2578523 | 0.80 | SGMS2 (0.54) | LMNAALDH1A1SGMS2CYP1A2CYP2C19 | |
| SCHEMBL7744533 | 0.80 | MAOB (0.51) | LMNAALDH1A1GAAABCB1CYP1A2 | |
| SCHEMBL2580792 | 0.80 | FFAR1 (0.48) | LMNAALDH1A1GAASGMS2ABCB1 | |
| SCHEMBL7369879 | 0.79 | NPC1 (0.51) | ALDH1A1GAACYP1A2CYP2D6MTNR1A | |
| SCHEMBL25750618 | 0.78 | ABCB1 (0.45) | LMNAALDH1A1GAASGMS2ABCB1 | |
| SCHEMBL4549105 | 0.78 | MAOB (0.54) | LMNAGAACYP1A2CYP2C19MAPT | |
| SCHEMBL2516365 | 0.78 | MAPT (0.52) | LMNAALDH1A1GAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783110-A1 | NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-09 | — | — | EP | disclosed |