Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477534 | 0.87 | DRD2 (0.55) | ALDH1A1SGMS2LMNADRD2DRD1 | |
| SCHEMBL2580244 | 0.85 | MAOB (0.55) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL2576276 | 0.84 | LMNA (0.52) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL25750670 | 0.83 | ABCB1 (0.53) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL25750618 | 0.83 | ABCB1 (0.45) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL11723955 | 0.82 | FFAR1 (0.57) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL2572231 | 0.82 | FFAR1 (0.48) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL2580792 | 0.82 | FFAR1 (0.48) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL28769510 | 0.82 | SGMS2 (0.56) | ABCB1ALDH1A1SGMS2LMNAGAA | |
| SCHEMBL1539311 | 0.82 | LIPE (0.45) | ALDH1A1SGMS2LMNAGAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212187-A1 | FUSED RING DERIVATIVES AND USE THEREOF IN PHARMACY | CISEN PHARMACEUTICAL CO., LTD (CN) | 2023-07-06 | — | — | US | disclosed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212187-A1 | FUSED RING DERIVATIVES AND USE THEREOF IN PHARMACY | ABCB1, CYP3A43, CYP3A7 | ABCB1 1/4885ALDH1A1 555/4885SGMS2 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.