SCHEMBL526705

SCHEMBL526705

Nc1ccc2cc(C(F)(F)F)c(=O)oc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 3/20 0.58
HPGD P15428 3/20 0.58
MEN1 O00255 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
HSD17B10 Q99714 2/20 0.58
SRC P12931 2/20 0.58
ATM Q13315 1/20 0.58
TLR9 Q9NR96 1/20 0.58
CA2 P00918 1/20 0.46
GLA P06280 3/20 0.43
POLB P06746 2/20 0.43
TSHR P16473 1/20 0.43
AR P10275 2/20 0.40
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15842332 0.81 PGR (0.43) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL12040002 0.80 CA12 (0.53) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL28642209 0.80 MAOB (0.47) KMT2AALDH1A1MEN1CA2AR
SCHEMBL106506 0.80 HSD17B3 (0.58) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL15842386 0.78 HTT (0.39) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL383681 0.77 HPGD (0.55) GAAKDM4EALDH1A1HPGDCASP1
SCHEMBL7544470 0.77 HPGD (0.55) GAAKDM4EALDH1A1HPGDCASP1
SCHEMBL16085333 0.77 SMN1; SMN2 (0.63) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL27935835 0.76 MEN1 (0.44) GAAKMT2AKDM4EALDH1A1HPGD
SCHEMBL1712282 0.76 MAOB (0.57) GAAKMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130203078-A1 NOVEL ULTRASENSITIVE CELL BASED SENSORS AND USES THEREOF CANVAX BIOTECH SL (ES) 2013-08-08 US claimed
EP-2598876-A1 NOVEL ULTRASENSITIVE CELL BASED SENSORS AND USES THEREOF Canvax Biotech SL (ES) 2013-06-05 EP claimed
WO-2012013204-A1 NOVEL ULTRASENSITIVE CELL BASED SENSORS AND USES THEREOF CANVAX BIOTECH SL (ES) 2012-02-02 WO claimed
US-20060281897-A1 Potentialization of the activation of high molecular weight prodrugs DIATOS S.A. (FR) 2006-12-14 US claimed
CN-122025633-A Polymeric adhesive for electrochemical cells including labels 通用汽车环球科技运作有限责任公司 2026-05-12 CN disclosed
EP-4619417-A1 NANOCONJUGATES CONTAINING PDGFR-BETA LIGANDS AND USES THEREOF Universitat Autònoma de Barcelona (ES) 2025-09-24 EP disclosed
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-26 US disclosed
EP-4493273-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES Politechnika Wroclawska (PL) 2025-01-22 EP disclosed
CN-118369344-A Anti-human CD45RC binding domain and uses thereof 阿博莱斯制药公司 2024-07-19 CN disclosed
WO-2024105116-A1 NANOCONJUGATES CONTAINING PDGFR-β LIGANDS AND USES THEREOF UNIVERSITAT AUTÒNOMA DE BARCELONA (ES) 2024-05-23 WO disclosed
WO-2023175356-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES POLITECHNIKA WROCLAWSKA (PL) 2023-09-21 WO disclosed
US-20230204587-A1 NOVEL DIAGNOSTIC MARKER FOR PROSTATE CANCER URTESTE S.A. (PL) 2023-06-29 US disclosed
WO-2000032044-A1 A NEW SUPPORT FOR HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY AND OTHER USES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-06-08 WO disclosed
WO-1999038993-A1 COMBINATORIAL QUINOLONE LIBRARY PHARMACOPEIA, INC. (US) 1999-08-05 WO disclosed
EP-0904401-A4 1999-05-12 EP disclosed
EP-0904401-A1 COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY PHARMACOPEIA, INC. (US) 1999-03-31 EP disclosed
US-5856083-A Lawn assay for compounds that affect enzyme activity or bind to target molecules PHARMACOPEIA, INC. (US) 1999-01-05 US disclosed
US-5766963-A IDENTIFYING BIOLOGICALLY ACTIVE MEMBERS BY SCREENING IN BIOASSAYS PHARMACOPEIA, INC. (US) 1998-06-16 US disclosed
WO-1997027315-A1 COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY PHARMACOPEIA, INC. (US) 1997-07-31 WO disclosed
WO-1997016569-A1 LAWN ASSAY FOR COMPOUNDS THAT AFFECT ENZYME ACTIVITY OR BIND TO TARGET MOLECULES PHARMACOPEIA, INC. (US) 1997-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES F11, F2, F12 GAA 932/4885KMT2A 2823/4885KDM4E 3069/4885
US-20060281897-A1 Potentialization of the activation of high molecular weight prodrugs CD44, MMP12, FOLH1 GAA 287/4885KMT2A 3864/4885KDM4E 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.