SCHEMBL29865804

SCHEMBL29865804

Nc1cccc(OC2(Oc3cccc(N)c3)C=CC(C(=O)c3ccccc3)=CC2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.44
MAOB P27338 2/20 0.37
STS P08842 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.32
LMNA P02545 2/20 0.32
MITF O75030 1/20 0.32
POLB P06746 1/20 0.32
AKR1C3 P42330 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAPK1 P28482 1/20 0.31
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390518 1.00 PBRM1 (0.44) PBRM1MAOBSTSMEN1KMT2A
SCHEMBL9750704 1.00 PBRM1 (0.44) PBRM1MAOBSTSMEN1KMT2A
SCHEMBL2154321 0.87 ALDH1A1 (0.37) STSMEN1KMT2AL3MBTL1ATM
SCHEMBL1627987 0.86 PBRM1 (0.35) PBRM1STSMEN1KMT2ANPC1
SCHEMBL10893916 0.82 TDP1 (0.40) MEN1KMT2ATDP1NPC1LMNA
SCHEMBL5267433 0.81 POLB (0.50) L3MBTL1TDP1LMNAPOLBAKR1C3
SCHEMBL3402558 0.81 PBRM1 (0.40) PBRM1MAOBSTSMEN1KMT2A
SCHEMBL9680944 0.80 MEN1 (0.40) STSMEN1KMT2ANPC1LMNA
SCHEMBL29720375 0.76 MAOB (0.41) MAOBMEN1KMT2AATMLMNA
SCHEMBL1270085 0.76 MAOB (0.41) MAOBMEN1KMT2AATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12074288-B2 Lithium secondary battery NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2024-08-27 US claimed
US-12107218-B2 Lithium secondary battery NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2024-10-01 US disclosed
US-12074288-B2 Lithium secondary battery NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2024-08-27 US disclosed
US-12074288-B2 Lithium secondary battery NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2024-08-27 US disclosed
WO-2023006987-A1 METHOD AND SYSTEM FOR MANUFACTURING AN ORTHOPAEDIC SPLINT AND ORTHOPAEDIC SPLINT THEREOF SKINCASTS (FR) 2023-02-02 WO disclosed
CN-115061581-A Chinese character input method 成巨才 2022-09-16 CN disclosed