Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12693795 | 0.70 | PPARG (0.43) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL1049364 | 0.70 | PPARG (0.43) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL1049898 | 0.70 | NPSR1 (0.44) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL1049365 | 0.70 | PPARG (0.43) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL1049897 | 0.70 | NPSR1 (0.44) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL997788 | 0.66 | ALPL (0.39) | ALDH1A1LMNASMN1; SMN2P2RX7HPGD | |
| SCHEMBL998544 | 0.65 | KDM4E (0.45) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL4092629 | 0.65 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL1048828 | 0.65 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 | |
| SCHEMBL997395 | 0.64 | NR1H2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | disclosed |