Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CDK14 | O94921 | 3/20 | 0.39 |
| ▸ | CCNY | Q8ND76 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269316 | 0.86 | CSNK2A1 (0.52) | CCNA2CDK2FLT3CCNA1CSNK2A1 | |
| SCHEMBL5270764 | 0.82 | KMT2A (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL5265233 | 0.82 | ALDH1A1 (0.44) | MAPTSMN1; SMN2ALDH1A1KMT2ATP53 | |
| SCHEMBL5269732 | 0.81 | SMN1; SMN2 (0.40) | MLKLSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL13816814 | 0.80 | FLT3 (0.49) | CCNA2CDK2FLT3CCNA1ATR | |
| SCHEMBL5268210 | 0.80 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5265937 | 0.79 | CCNE2 (0.45) | CDK2MAPTSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5271610 | 0.79 | MEN1 (0.57) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5267186 | 0.79 | NAPRT (0.51) | CCNA2CDK2FLT3CCNA1MAPT | |
| SCHEMBL5267179 | 0.78 | KMT2A (0.50) | MAPTATRSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |