Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268993 | 0.87 | ALDH1A1 (0.54) | ALDH1A1POLBPKMGAASMN1; SMN2 | |
| SCHEMBL5267514 | 0.83 | F2 (0.46) | ALDH1A1GAASMN1; SMN2MAPTTP53 | |
| SCHEMBL5268485 | 0.83 | KCNA5 (0.51) | ALDH1A1GAAMAPTTP53KMT2A | |
| SCHEMBL5268923 | 0.82 | ALDH1A1 (0.47) | ALDH1A1POLBPKMSMN1; SMN2MAPT | |
| SCHEMBL5267963 | 0.82 | MLKL (0.43) | ALDH1A1SMN1; SMN2MAPTTP53KMT2A | |
| SCHEMBL13816854 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBPKMGAAMAPT | |
| SCHEMBL5270827 | 0.81 | KMT2A (0.58) | ALDH1A1POLBGAASMN1; SMN2MAPT | |
| SCHEMBL5267465 | 0.81 | AR (0.43) | ALDH1A1POLBPKMGAASMN1; SMN2 | |
| SCHEMBL5272580 | 0.80 | ALOX15 (0.49) | ALDH1A1POLBPKMGAAMAPT | |
| SCHEMBL5269046 | 0.80 | KCNA5 (0.50) | ALDH1A1GAAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |