Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 13/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274062 | 0.88 | L3MBTL1 (0.42) | ALDH1A1HPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL5268810 | 0.80 | MAPT (0.52) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5272585 | 0.80 | MAPT (0.44) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5268786 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5334971 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5265090 | 0.79 | MAPT (0.66) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5273322 | 0.78 | GABRA1 (0.49) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5268590 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5270537 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5271355 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |