Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | SNCA | P37840 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268321 | 1.00 | CYP1A2 (0.45) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL5268330 | 1.00 | CYP1A2 (0.45) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL24126375 | 0.80 | CYP1A2 (0.49) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL6896309 | 0.79 | CYP1A2 (0.53) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL6896312 | 0.79 | CYP1A2 (0.53) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL22125376 | 0.78 | CYP1A2 (0.51) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL22125377 | 0.78 | CYP1A2 (0.51) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL7898750 | 0.77 | CYP1A2 (0.57) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL7898751 | 0.77 | CYP1A2 (0.57) | CYP1A2HAO1ALDH1A1PTGS1SLCO1B3 | |
| SCHEMBL10636871 | 0.76 | ALDH1A1 (0.41) | CYP1A2ALDH1A1PTGS1SLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442014-B1 | MANUFACTURE OF RETINOIDS | DSM IP ASSETS BV (NL) | 2007-03-21 | — | — | EP | disclosed |
| US-7067703-B2 | Manufacture of retinoids | DSM IP ASSETS B.V. (NL) | 2006-06-27 | — | — | US | disclosed |
| US-20050014976-A1 | Manufacture of retinoids | DSM IP ASSETS B.V. (NL) | 2005-01-20 | — | — | US | disclosed |
| EP-1442014-A1 | MANUFACTURE OF RETINOIDS | DSM IP Assets B.V. (NL) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037856-A1 | MANUFACTURE OF RETINOIDS | DSM IP ASSETS B.V. (NL) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014976-A1 | Manufacture of retinoids | RXRA, ALDH1A2, RXRB | CYP1A2 516/4885HAO1 680/4885ALDH1A1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.