Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270560 | 0.87 | LMNA (0.54) | LMNAMAPTTDP1TP53POLB | |
| SCHEMBL5269318 | 0.85 | LMNA (0.53) | LMNAMAPTTDP1TP53POLB | |
| SCHEMBL5269706 | 0.83 | LMNA (0.55) | LMNAMAPTTP53POLBMEN1 | |
| SCHEMBL5272339 | 0.83 | LMNA (0.54) | LMNAMAPTTDP1POLBMEN1 | |
| SCHEMBL5270115 | 0.83 | LMNA (0.54) | LMNAMAPTPOLBKCNA5SMN1; SMN2 | |
| SCHEMBL5266716 | 0.83 | LMNA (0.69) | LMNAMAPTTDP1TP53POLB | |
| SCHEMBL5271687 | 0.83 | KCNA5 (0.56) | LMNAMAPTTDP1TP53POLB | |
| SCHEMBL5268976 | 0.83 | MEN1 (0.49) | LMNAMAPTTDP1POLBL3MBTL1 | |
| SCHEMBL5269789 | 0.83 | MEN1 (0.51) | LMNAMAPTTDP1POLBL3MBTL1 | |
| SCHEMBL5268784 | 0.82 | NPC1 (0.47) | LMNAMEN1KMT2AKCNA5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |