SCHEMBL5268533

SCHEMBL5268533

O=Cc1ccccc1-c1cccc(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.60
KMO O15229 1/20 0.58
UNG P13051 1/20 0.51
ALDH1A1 P00352 2/20 0.51
POLB P06746 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
FOLH1 Q04609 2/20 0.51
KDM4E B2RXH2 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
DDT P30046 1/20 0.50
PTGER1 P34995 1/20 0.49
NR1H4 Q96RI1 1/20 0.48
PLA2G2A P14555 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4263608 0.98 ERN1 (0.59) ERN1KMOUNGALDH1A1POLB
SCHEMBL2556740 0.87 ERN1 (0.61) ERN1KMOUNGALDH1A1POLB
SCHEMBL27966305 0.85 KMO (0.56) ERN1KMOALDH1A1POLBL3MBTL1
SCHEMBL2213546 0.84 KMO (0.73) KMOFOLH1DDTPTGER1NR1H4
SCHEMBL30259065 0.84 KMO (0.73) KMOFOLH1DDTPTGER1NR1H4
SCHEMBL382724 0.82 KMO (0.70) KMOFOLH1DDTPTGER1NR1H4
SCHEMBL1707626 0.82 KMO (0.70) KMOFOLH1DDTPTGER1NR1H4
SCHEMBL3556722 0.81 ERN1 (0.53) ERN1ALDH1A1FOLH1KDM4ETDP1
SCHEMBL29950910 0.81 ERN1 (0.53) ERN1ALDH1A1FOLH1KDM4ETDP1
SCHEMBL2574399 0.81 ERN1 (0.47) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325542-A1 INHIBITORS OF ANTIMOCROBIAL RESISTANCE AND METHOS USING SAME BAYLOR COLLEGE MEDICINE (US) 2025-10-23 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-1841428-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES Immusol Incorporated (US) 2007-10-10 EP disclosed
WO-2006078754-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES IMMUSOL INCORPORATED (US) 2006-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325542-A1 INHIBITORS OF ANTIMOCROBIAL RESISTANCE AND METHOS USING SAME BPGM, PNMT, DDT ERN1 2616/4885KMO 89/4885UNG 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.