Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852245 | 1.00 | BRD4 (0.53) | BRD4KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL13348591 | 0.86 | BRD4 (0.53) | BRD4KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1707917 | 0.84 | KDM4E (0.53) | BRD4KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL17028439 | 0.84 | L3MBTL1 (0.53) | KMT2ASMN1; SMN2LMNAMAPTTDP1 | |
| SCHEMBL31471103 | 0.83 | BRD4 (0.60) | BRD4KMT2AMEN1POLBPDE4A | |
| SCHEMBL27492257 | 0.82 | BRD4 (0.58) | BRD4MAPTPDE4ATDP2CYP1A2 | |
| SCHEMBL29781451 | 0.80 | RAB9A (0.40) | KMT2AMEN1SMN1; SMN2LMNAMAPT | |
| SCHEMBL31307011 | 0.80 | BRD4 (0.53) | BRD4POLBLMNAMAPTPDE4A | |
| SCHEMBL13313473 | 0.79 | BRD4 (0.56) | BRD4PDE4ATDP1TDP2RAB9A | |
| SCHEMBL7267932 | 0.79 | BRD4 (0.56) | BRD4SMN1; SMN2PDE4ATDP1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |