Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5268861 | 1.00 | PDE4B (0.39) | PDE4BL3MBTL1ALDH1A1PKMPDE4D | |
| SCHEMBL3550102 | 0.89 | PDK2 (0.43) | PDE4BALDH1A1PDE4D | |
| SCHEMBL3550103 | 0.89 | PDK2 (0.43) | PDE4BALDH1A1PDE4D | |
| SCHEMBL3544576 | 0.88 | MMP2 (0.36) | PDE4BALDH1A1PDE4D | |
| SCHEMBL3544577 | 0.88 | MMP2 (0.36) | PDE4BALDH1A1PDE4D | |
| Hydroxyamine SCHEMBL3621021 | 0.79 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL3544265 | 0.79 | FKBP1A (0.51) | ALDH1A1GAA | |
| Hydroxyamine SCHEMBL3621023 | 0.79 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL3544267 | 0.79 | FKBP1A (0.51) | ALDH1A1GAA | |
| Hydroxyamine SCHEMBL5274861 | 0.78 | GAA (0.53) | L3MBTL1ALDH1A1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |