Metamitron

Metamitron

SCHEMBL5268872

CSc1nnc(C(C)(C)C)c(=O)n1N.Cc1nnc(-c2ccccc2)c(=O)n1N

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
ALDH1A1 P00352 5/20 0.48
GAA P10253 3/20 0.40
KDM4E B2RXH2 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 3/20 0.37
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metamitron SCHEMBL11409806 0.84 KDM4E (0.43) HPGDALDH1A1GAAKDM4ESMN1; SMN2
SCHEMBL10508760 0.84 ALDH1A1 (0.61) HPGDALDH1A1KDM4ESMN1; SMN2KMT2A
Metamitron SCHEMBL8536394 0.80 KDM4E (0.49) ALDH1A1GAAKDM4ESMN1; SMN2KMT2A
Metamitron SCHEMBL66369 0.80 KDM4E (0.49) ALDH1A1GAAKDM4ESMN1; SMN2KMT2A
Hexazinone SCHEMBL4659858 0.79 MEN1 (0.35) HPGDALDH1A1GAASMN1; SMN2KMT2A
Metribuzin SCHEMBL8535922 0.78 HPGD (0.51) HPGDALDH1A1GAAKDM4ESMN1; SMN2
Metribuzin SCHEMBL66824 0.78 HPGD (0.51) HPGDALDH1A1GAAKDM4ESMN1; SMN2
Metribuzin SCHEMBL20723898 0.77 HPGD (0.50) HPGDALDH1A1GAAKDM4ESMN1; SMN2
Metribuzin SCHEMBL20723685 0.77 HPGD (0.50) HPGDALDH1A1GAAKDM4ESMN1; SMN2
Metribuzin SCHEMBL11404778 0.76 HPGD (0.53) HPGDALDH1A1GAAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765072-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS Akzo Nobel N.V. (NL) 2007-03-28 EP disclosed
WO-2006019772-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS AKZO NOBEL N.V. (NL) 2006-02-23 WO disclosed
WO-2003055959-A1 LOW-DUST SOLID FUEL PREPARATIONS BAYER CHEMICALS AG (DE) 2003-07-10 WO disclosed
WO-1999002660-A1 CATALYTIC ANTIBODIES FOR THE INACTIVATION OF HERBICIDES KEINAN EHUD (IL) 1999-01-21 WO disclosed
EP-0003890-B2 Herbicidal pyridine compounds and herbicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-04 EP disclosed
WO-1979000733-A1 HETEROCYCLIC COMPOUNDS ICI LTD (GB) 1979-10-04 WO disclosed
WO-1979000624-A1 HERBICIDAL DERIVATIVES OF 2-(4(2-PYRIDYLOXY)PHENOXY)PROPANE,PROCESSES FOR PREPARING THEM,AND HERBICIDAL COMPOSITIONS CONTAINING THEM ICI LTD (GB) 1979-09-06 WO disclosed
EP-0003648-A2 4-Aryloxy-substituted phenoxypropionamide derivatives useful as herbicides, compositions containing them, and processes for making them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-22 EP disclosed