Metribuzin

Metribuzin

SCHEMBL66824

CSc1nnc(C(C)(C)C)c(=O)n1N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.51
GAA P10253 4/20 0.40
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 3/20 0.38
MAPK1 P28482 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSP90AA1 P07900 1/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metribuzin SCHEMBL8535922 1.00 HPGD (0.51) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL27754192 0.98 HPGD (0.50) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL20723685 0.98 HPGD (0.50) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL20723898 0.98 HPGD (0.50) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL11004013 0.93 HPGD (0.47) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL11404778 0.93 HPGD (0.53) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL20564231 0.92 HPGD (0.46) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL22715491 0.92 HPGD (0.49) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL27813761 0.92 HPGD (0.46) HPGDGAAKDM4EALDH1A1POLB
Metribuzin SCHEMBL368282 0.92 HPGD (0.52) HPGDGAAKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27189 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144260-A1 COMPOSITION AND METHOD FOR IMPROVING AGRONOMIC TRAITS OF A PLANT THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-05-28 US claimed
CN-122056948-A Uncaria alkaloid extract and preparation method and application thereof 华南理工大学 2026-05-19 CN claimed
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN claimed
WO-2026099727-A1 SYNERGISTIC HERBICIDAL COMPOSITION FOR CONTROLLING WEEDS BPI CHEMTEX PRIVATE LIMITED (IN) 2026-05-15 WO claimed
US-20260130373-A1 EMULSIFIABLE CONCENTRATE (EC) SYNGENTA CROP PROTECTION AG (CH) 2026-05-14 US claimed
CN-122004229-A Ternary weeding composition and application thereof 山东清原农冠作物科学有限公司 2026-05-12 CN claimed
US-12616199-B2 Crystallisation-free, highly concentrated suspension concentrates of metribuzin and diflufenican BAYER AKTIENGESELLSCHAFT (DE) 2026-05-05 US claimed
WO-2026088192-A1 METHOD FOR CONTROLLING WEED IN CEREAL CROPS ADAMA AGAN LTD. (IL) 2026-04-30 WO claimed
WO-2026088132-A1 COMPOSITIONS COMPRISING SEAWEED EXTRACT UPL MAURITIUS LIMITED (MU) 2026-04-30 WO claimed
US-12610950-B2 Method for weed control in lawn or turf DISCOVERY PURCHASER CORPORATION (US) 2026-04-28 US claimed
US-4256481-A Selective herbicide compositions NITROKEMIA IPARTELEPEK (HU) 1981-03-17 US claimed
US-4225693-A CONTROLLED RELEASE HOPKINS AGRICULTURAL CHEMICAL COMPANY 1980-09-30 US claimed
EP-0007112-A2 Flowable defoliant and desiccant composition and its use J.T. Baker Chemical Co. (US) 1980-01-23 EP claimed
US-4168152-A TRIAZINE HERBICIDES WITH N-BENZENESULFONYL CARBAMATES AS HERBICIDE ANTIBOTES STAUFFER CHEMICAL COMPANY (US) 1979-09-18 US claimed
US-4150968-A HERBICIDES MOBAY CHEMICAL CORPORATION (US) 1979-04-24 US claimed
US-4095972-A Herbicidal composition of particular triazinone and diphenyl ether BAYER AKTIENGESELLSCHAFT (DT) 1978-06-20 US claimed
US-4035364-A Methyl bromide thiol methylation of mercapto group of 4-amino-6-t.-butyl-3-mercapto-1,2,4-triazin-5-one BAYER AKTIENGESELLSCHAFT (DT) 1977-07-12 US claimed
US-4032324-A 1,2,4-TRIAZIN-5-ONES AND DICHLOROPHENYL-N,N-DIMETHYL-UREA BAYER AKTIENGESELLSCHAFT (DT) 1977-06-28 US claimed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US claimed
US-3986862-A EMULSIFIABLE LIQUID CONCENTRATES CONTAINING 4-AMINO-6-T-BUTYL-3-(METHYLTHIO)-1,2,4-TRIAZIN-5-ONE AND 2-CHLORO-N-(2,6-DIETHYLPHENYL)-N-METHOXYMETHYLACETAMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 US claimed