SCHEMBL5268934

SCHEMBL5268934

Cc1ccccc1OC(CCCO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.46
PPARA Q07869 10/20 0.46
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 3/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2D6 P10635 3/20 0.41
SLC6A2 P23975 3/20 0.41
CHRM1 P11229 2/20 0.41
TSHR P16473 2/20 0.41
ADRA2B P18089 2/20 0.41
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
SLC6A4 P31645 2/20 0.41
HRH1 P35367 2/20 0.41
OPRM1 P35372 2/20 0.41
DRD3 P35462 2/20 0.41
OPRK1 P41145 2/20 0.41
HTR2B P41595 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KCNH2 Q12809 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14565994 0.85 CTRC (0.50) PPARGPPARATDP1CYP3A4OPRK1
SCHEMBL5718636 0.85 KMT2A (0.55) PPARGPPARACYP1A2CYP3A4CYP2D6
SCHEMBL3978158 0.83 PPARG (0.47) PPARGPPARATDP1CYP1A2CYP3A4
SCHEMBL8935641 0.81 SMN1; SMN2 (0.57) PPARGPPARATDP1TSHRKDM4E
SCHEMBL3879629 0.81 SMN1; SMN2 (0.57) PPARGPPARATDP1TSHRKDM4E
SCHEMBL9623318 0.77 TDP1 (0.49) PPARGPPARATDP1KMT2APTGES
SCHEMBL8563940 0.76 PPARG (0.46) PPARGPPARA
SCHEMBL8563944 0.76 PPARG (0.46) PPARGPPARA
SCHEMBL28490552 0.75 PPARG (0.49) PPARGPPARATDP1PTGESALOX5
SCHEMBL30639267 0.75 CTRC (0.54) PPARGPPARACYP3A4OPRK1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 US claimed
EP-1167507-B1 Malodor counteractant compositions and methods for preparing and using same BUSH BOAKE ALLEN INC (US) 2007-10-10 EP disclosed
US-6432891-B1 INTRODUCING INTO SOLID OR LIQUID, SOAP OR DETERGENT COMPOUND SELECTED FROM 1-CYCLOHEXYL-ETHYLBUTYRATE, 1-CYCLOHEXYL-ETHYLACETATE, 1-CYCLOHEXYL-ETHANOL, 4-ISOPROPYL-CYCLOHEXYLPROPIONATE BUSH BOAKE ALLEN INC., 2002-08-13 US disclosed
US-20020032131-A1 Malodor counteractant compositions and methods for preparing and using same BUSH BOAKE ALLEN INC. 2002-03-14 US disclosed
EP-1167507-A2 Malodor counteractant compositions and methods for preparing and using same Bush Boake Allen Inc. (US) 2002-01-02 EP disclosed