Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002707 | 0.85 | TNKS2 (0.43) | MAOBACHECA12CA9HSD17B3 | |
| SCHEMBL719067 | 0.78 | MCL1 (0.55) | MCL1MAOBAKR1B1KDM4EALDH1A1 | |
| SCHEMBL14809632 | 0.77 | HPGD (0.44) | MAOBACHEHSD17B3KDM4EALDH1A1 | |
| SCHEMBL18003048 | 0.75 | PGR (0.46) | MAOBCA12CA9KDM4EALDH1A1 | |
| SCHEMBL3500950 | 0.75 | MCL1 (0.60) | MCL1CA12CA9HSD17B3KDM4E | |
| SCHEMBL3498475 | 0.75 | MCL1 (0.78) | MCL1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL719541 | 0.74 | MAOB (0.44) | MAOBACHEHSD17B3PTPN1 | |
| SCHEMBL3501203 | 0.74 | MCL1 (0.58) | MCL1MAOAMAOBACHECA12 | |
| SCHEMBL3501204 | 0.74 | MCL1 (0.58) | MCL1CA1CA2CA12CA9 | |
| SCHEMBL11760949 | 0.71 | PTPN1 (0.49) | MCL1KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |