SCHEMBL5269441

SCHEMBL5269441

CCCCCCCCCCCCCCCCCCCCc1ccc(C(=O)O)c(O)c1O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.56
TYR P14679 1/20 0.54
KAT8 Q9H7Z6 4/20 0.53
BID P55957 3/20 0.53
MCL1 Q07820 3/20 0.53
BCL2L1 Q07817 2/20 0.53
BAK1 Q16611 2/20 0.53
PPARG P37231 2/20 0.53
EP300 Q09472 1/20 0.53
KAT2A Q92830 1/20 0.53
KAT2B Q92831 1/20 0.53
KAT5 Q92993 1/20 0.53
SAE1 Q9UBE0 1/20 0.53
RARA P10276 1/20 0.48
RARB P10826 1/20 0.48
RARG P13631 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17625912 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL5268382 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL5268409 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL5270072 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL17625900 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL28465098 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL5272862 1.00 PPARA (0.56) PPARATYRKAT8BIDMCL1
SCHEMBL7521299 0.98 PPARA (0.54) PPARATYRKAT8BIDMCL1
SCHEMBL11868796 0.87 PPARA (0.54) PPARATYRKAT8BIDMCL1
SCHEMBL7568852 0.87 BID (0.57) PPARATYRKAT8BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243609-B1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO (JP) 2007-10-24 EP disclosed
US-6906191-B2 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2005-06-14 US disclosed
US-20030018198-A1 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2003-01-23 US disclosed
EP-1243609-A1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2002-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018198-A1 Succinimide compounds and use thereof SRM, SMS, SGMS2 PPARA 681/4885TYR 3411/4885KAT8 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.