Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516551 | 0.87 | F10 (0.47) | TP53LMNAMAPTENPP2ALDH1A1 | |
| SCHEMBL4516548 | 0.87 | F10 (0.47) | TP53LMNAMAPTENPP2ALDH1A1 | |
| SCHEMBL5266162 | 0.85 | F10 (0.42) | TP53LMNAMAPTKDM4EENPP2 | |
| SCHEMBL5264221 | 0.81 | TP53 (0.41) | TP53LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL2765417 | 0.80 | LMNA (0.42) | TP53LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL2766124 | 0.76 | LMNA (0.44) | TP53LMNAMAPTKDM4E | |
| SCHEMBL2767435 | 0.75 | LMNA (0.48) | TP53LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL2765569 | 0.75 | LMNA (0.46) | TP53LMNAMAPTKDM4E | |
| SCHEMBL2767137 | 0.75 | LMNA (0.46) | TP53LMNAMAPTKDM4E | |
| SCHEMBL5267348 | 0.73 | POLB (0.40) | TP53LMNAMAPTENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |