SCHEMBL5269729

SCHEMBL5269729

CS(=O)(=O)C1CCN([C]=O)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.32
SMO Q99835 1/20 0.31
LTA4H P09960 1/20 0.31
USP30 Q70CQ3 3/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3953742 0.87 USP30 (0.32) ACHEUSP30
SCHEMBL4176592 0.87 USP30 (0.32) ACHEUSP30
SCHEMBL4173641 0.87 USP30 (0.32) ACHEUSP30
SCHEMBL12239181 0.81 SMO (0.33) ACHESMOLTA4HIDO1
SCHEMBL21112514 0.76 ACHE (0.30) ACHE
SCHEMBL357188 0.73 NCF1 (0.37) IDO1
SCHEMBL12706336 0.73 TP53 (0.33) IDO1
SCHEMBL23155733 0.71 IDO1 (0.31) ACHESMOLTA4HIDO1
Hydrochloric Acid SCHEMBL1902055 0.71 NCF1 (0.36) IDO1
SCHEMBL19195506 0.71 IDO1 (0.31) ACHESMOLTA4HIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1771456-A2 HYBRID QA MOLECULES WHEREIN Q IS AN AMINOQUINOLINE AND A IS AN ANTIBIOTIC RESIDUE, THEIR SYNTHESIS AND THEIR USES AS ANTIBACTERIAL AGENT Palumed SA (FR) 2007-04-11 EP disclosed
WO-2006024741-A2 HYBRID QA MOLECULES WHEREIN Q IS AN AMINOQUINOLINE AND A IS AN ANTIBIOTIC RESIDUE, THEIR SYNTHESIS AND THEIR USES AS ANTIBACTERIAL AGENT PALUMED S.A. (FR) 2006-03-09 WO disclosed