⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580985 | 0.87 | SLC6A1 (0.50) | — | |
| SCHEMBL1643324 | 0.86 | GABRA5 (0.48) | — | |
| SCHEMBL688937 | 0.80 | — | — | |
| SCHEMBL184224 | 0.80 | — | — | |
| SCHEMBL436562 | 0.80 | — | — | |
| SCHEMBL6181576 | 0.80 | — | — | |
| SCHEMBL3155834 | 0.80 | — | — | |
| SCHEMBL435813 | 0.80 | — | — | |
| SCHEMBL3145317 | 0.80 | — | — | |
| SCHEMBL8141975 | 0.79 | SLC6A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998023626-A1 | ANTIADHESIVE BENZOIC ACID DERIVATIVES | GLYCOREX AB (SE) | 1998-06-04 | — | — | WO | claimed |
| EP-0578535-B1 | New peptide derivates active in the process of cell adhesion, a method to prepare them end pharmaceutical compositions containing them | ADIR (FR) | 1996-08-21 | — | — | EP | claimed |
| EP-0300462-B1 | HETEROCYCLIC PEROXYCARBOXYLIC ACIDS | AUSIMONT S.p.A. (IT) | 1993-09-29 | — | — | EP | claimed |
| EP-2627631-A1 | PYRROLIDINONES AS METAP2 INHIBITORS | Merck Patent GmbH (DE) | 2013-08-21 | — | — | EP | disclosed |
| EP-1836180-B1 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2012-06-13 | — | — | EP | disclosed |
| WO-2012048775-A1 | PYRROLIDINONES AS METAP2 INHIBITORS | MERCK PATENT GMBH (DE) | 2012-04-19 | — | — | WO | disclosed |
| EP-1836180-A2 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | sanofi-aventis (FR) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006072393-A2 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI-AVENTIS (DE) | 2006-07-13 | — | — | WO | disclosed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-1998023626-A1 | ANTIADHESIVE BENZOIC ACID DERIVATIVES | GLYCOREX AB (SE) | 1998-06-04 | — | — | WO | disclosed |
| EP-0475156-A1 | Substituted 3-aminosydnonimines, method for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |