Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AOC1 | P19801 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963848 | 0.82 | TBXAS1 (0.49) | TSHRALDH1A1CYP3A4GABRA1NFKB1 | |
| SCHEMBL6665692 | 0.81 | AOC1 (0.43) | TSHRALDH1A1CYP3A4GABRA1NFKB1 | |
| SCHEMBL23704534 | 0.81 | AOC1 (0.43) | TSHRALDH1A1CYP3A4GABRA1NFKB1 | |
| SCHEMBL30979850 | 0.77 | AOC1 (0.43) | TSHRALDH1A1CYP3A4GABRA1NFKB1 | |
| SCHEMBL8820702 | 0.76 | NPC1 (0.47) | TSHRALDH1A1CYP3A4GABRA1NFKB1 | |
| SCHEMBL23124259 | 0.76 | — | — | |
| SCHEMBL5217908 | 0.76 | — | — | |
| SCHEMBL2916977 | 0.75 | HRH2 (0.47) | ALDH1A1TBXAS1MAPTHRH3KMT2A | |
| SCHEMBL10622903 | 0.75 | HRH2 (0.47) | ALDH1A1TBXAS1MAPTHRH3KMT2A | |
| SCHEMBL4186059 | 0.75 | HRH2 (0.47) | ALDH1A1TBXAS1MAPTHRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333114-A | ST2 antigen binding proteins | 安进公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-109206517-B | ST2 antigen binding proteins | 安进公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-1303291-B1 | ANTI-HIV AND ANTI-TUMOR PEPTIDES AND FRAGMENTS OF LYSOZYME | UNIV NEW YORK (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1303291-A4 | ANTI-HIV AND ANTI-TUMOR PEPTIDES AND FRAGMENTS OF LYSOZYME | UNIV NEW YORK (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1016414-B1 | Human growth hormone to stimulate hematopoiesis and immune reconstitution after hematopoietic stem cell transplantation in humans | APPLIED RESEARCH SYSTEMS (AN) | 2004-09-08 | — | — | EP | disclosed |
| EP-1223970-A4 | SHORT SEGMENTS OF DAP-KINASE | YEDA RES & DEV (IL) | 2003-05-07 | — | — | EP | disclosed |
| EP-1303291-A1 | ANTI-HIV AND ANTI-TUMOR PEPTIDES AND FRAGMENTS OF LYSOZYME | NEW YORK UNIVERSITY (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020103353-A1 | Nucleotide sequences coding preferential polypeptide for use in the traetment of injuries caused by hypoxia, ischemia and stroke | QUARK PHARMACEUTICALS, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2001026678-A9 | SHORT SEGMENTS OF DAP-KINASE | YEDA RES & DEV (IL) | 2002-08-01 | — | — | WO | disclosed |
| EP-1223970-A1 | SHORT SEGMENTS OF DAP-KINASE | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2002-07-24 | — | — | EP | disclosed |
| WO-2002050273-A2 | A TRANSMEMBRANE PROTEIN AS A DOWNSTREAM TARGET OF NEUROTROPHIN AND EPHRIN RECEPTOR TYROSINE KINASES, DNA ENCODING SAME MONOCLONAL ANTIBODIES THERETO | NEW YORK UNIVERSITY (US) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002024929-A2 | A SOLUBLE BETA 2 MICROGLOBULIN (β2M)/HFE MONOCHAIN FOR BIOTECHNOLOGICAL AND THERAPEUTIC APPLICATIONS | RAMOT AT TEL AVIV UNIVERSITY LTD (IL) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002004011-A1 | ANTI-HIV AND ANTI-TUMOR PEPTIDES AND FRAGMENTS OF LYSOZYME | NEW YORK UNIVERSITY (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2001026678-A1 | SHORT SEGMENTS OF DAP-KINASE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2001-04-19 | — | — | WO | disclosed |
| WO-1999066030-A9 | DAP-KINASE RELATED PROTEIN | YEDA RES & DEV (IL) | 2000-07-06 | — | — | WO | disclosed |
| EP-1016414-A2 | Human growth hormone to stimulate hematopoiesis and immune reconstitution after hematopoietic stem cell transplantation in humans | Applied Research Systems ARS Holding N.V. (AN) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999066030-A1 | DAP-KINASE RELATED PROTEIN | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 1999-12-23 | — | — | WO | disclosed |