Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | AOC1 | P19801 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622903 | 0.91 | HRH2 (0.47) | TBXAS1HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL2916977 | 0.91 | HRH2 (0.47) | TBXAS1HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL2913102 | 0.91 | HRH2 (0.47) | TBXAS1HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL4186059 | 0.91 | HRH2 (0.47) | TBXAS1HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL2916182 | 0.91 | HRH2 (0.47) | TBXAS1HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL10625908 | 0.83 | SLC6A5 (0.54) | ALDH1A1CYP3A4TSHRKDM4ECYP19A1 | |
| SCHEMBL23704534 | 0.82 | AOC1 (0.43) | TBXAS1AOC1HRH3NPC1RAB9A | |
| SCHEMBL5269768 | 0.82 | TSHR (0.50) | TBXAS1AOC1HRH3NPC1RAB9A | |
| SCHEMBL6665692 | 0.82 | AOC1 (0.43) | AOC1HRH3NPC1RAB9ATP53 | |
| SCHEMBL10623012 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRKDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525621-A | CARDIOVASCULAR DISORDERS; ANTIINFLAMMATORY AGENTS | CYTOS PHARMACEUTICALS LLC (US) | 1996-06-11 | — | — | US | disclosed |