Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495647 | 0.86 | NOTUM (0.63) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL22248030 | 0.84 | NOTUM (0.66) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL526097 | 0.84 | NOTUM (0.49) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5860023 | 0.81 | MEN1 (0.68) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL31427175 | 0.80 | MEN1 (1.00) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7824829 | 0.80 | MEN1 (1.00) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL19150407 | 0.80 | MEN1 (0.67) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28003949 | 0.78 | MEN1 (0.79) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL525875 | 0.78 | MAPT (0.46) | NOTUMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11061527 | 0.77 | KMT2A (0.49) | NOTUMMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014186-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN AND ITS NOVEL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |