Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.39 |
| ▸ | KDM5C | P41229 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296509 | 1.00 | LMNA (0.46) | LMNASLC15A2EGLN1NPSR1MEN1 | |
| SCHEMBL7824361 | 0.77 | LMNA (0.50) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL7824359 | 0.77 | LMNA (0.50) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL23829487 | 0.72 | — | — | |
| SCHEMBL1408433 | 0.72 | — | — | |
| SCHEMBL29264685 | 0.72 | — | — | |
| SCHEMBL27623600 | 0.72 | NPSR1 (0.48) | NPSR1MEN1KMT2APMP22TSHR | |
| Succinic Acid SCHEMBL2148509 | 0.69 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL35204 | 0.69 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL16415716 | 0.69 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221447-B1 | Alkyl Cobalt (III) Dioximates and process for forming the same | DU PONT (US) | 2007-10-03 | — | — | EP | disclosed |
| US-6858745-B2 | Alkyl cobalt (III) dioximates and process for forming the same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-6740618-B2 | REACTIN A GLYOXIME, A COBALT SALT, AN UNSATURATED COMPOUND SUCH AS AN ALKYL ACRYLATE, AND A LEWIS BASE IN H2; USE AS A POLYMERIZATION CATALYST, ESPECIALLY IN POLYMERIZING METHYL METHACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-05-25 | — | — | US | disclosed |
| US-6713427-B2 | TREATING A MIXTURE OF A COBALT (II) SALT, A DIOXIME OF THE FORMULA R1-C( HORIZONTAL-LINE NOH)-C( HORIZONTAL-LINE NOH)-R2, AN ACRYLIC ESTER, A LEWIS BASE WITH MOLECULAR HYDROGEN TO FORM A COBALT DIOXIMATE COMPLEX | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-30 | — | — | US | disclosed |
| US-20030149275-A1 | Alkyl cobalt (III) dioximates and process for forming the same | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-08-07 | — | — | US | disclosed |
| US-20030135054-A1 | Alkyl cobalt(III) dioximates and process for forming the same | GRIDNEV ALEXEI A (US) | 2003-07-17 | — | — | US | disclosed |
| US-20030125564-A1 | Alkyl cobalt (III) dioximates and process for forming the same | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-07-03 | — | — | US | disclosed |
| US-6559327-B2 | By reacting a cobalt salt, a dioxime such as diphenylglyoxime, a lewis base such as 1,2-dimethylimidazole, and an olefinic compound such as methyl acrylate, and treating with hydrogen; high yield, purity | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-05-06 | — | — | US | disclosed |
| EP-1221447-A2 | Alkyl Cobalt (III) Dioximates and process for forming the same | E. I. du Pont de Nemours and Company (US) | 2002-07-10 | — | — | EP | disclosed |
| US-20020087006-A1 | Alkyl cobalt (III) dioximates and process for forming the same | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2002-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149275-A1 | Alkyl cobalt (III) dioximates and process for forming the same | CCR3, CBR3, CCR6 | LMNA 4147/4885SLC15A2 1312/4885EGLN1 1623/4885 |
| US-20030125564-A1 | Alkyl cobalt (III) dioximates and process for forming the same | CCR3, CBR3, CCR6 | LMNA 4165/4885SLC15A2 1323/4885EGLN1 1634/4885 |
| US-20020087006-A1 | Alkyl cobalt (III) dioximates and process for forming the same | CCR3, CBR3, CCR6 | LMNA 4165/4885SLC15A2 1323/4885EGLN1 1634/4885 |
| US-20030135054-A1 | Alkyl cobalt(III) dioximates and process for forming the same | CCR3, CBR3, CCR6 | LMNA 4165/4885SLC15A2 1323/4885EGLN1 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.