Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623874 | 0.83 | HPGD (0.50) | IMPDH2HTR2CPLAUCLK1HTR2A | |
| SCHEMBL3263472 | 0.78 | HTR2C (0.59) | HTR2CHTR2AHPGDCYP2C19TSHR | |
| SCHEMBL4185239 | 0.76 | HTR2A (0.53) | IMPDH2HTR2CHTR2AHPGDCYP2C19 | |
| SCHEMBL28181335 | 0.75 | IMPDH2 (0.51) | IMPDH2HTR2CASH1LCLK1CDK5 | |
| SCHEMBL13537216 | 0.75 | IMPDH2 (0.50) | IMPDH2ASH1LCLK1CDK5CDK5R1 | |
| SCHEMBL22777972 | 0.75 | IMPDH2 (0.50) | IMPDH2HTR2CASH1LCLK1CDK5 | |
| SCHEMBL395010 | 0.75 | ATM (0.52) | IMPDH2ASH1LCLK1CDK5CDK5R1 | |
| SCHEMBL2804219 | 0.75 | CYP2A6 (0.55) | IMPDH2CLK1CDK5CDK5R1 | |
| SCHEMBL21623869 | 0.75 | HTR2A (0.56) | HTR2CHTR2AKIF11 | |
| SCHEMBL1931747 | 0.75 | GPR84 (0.63) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781379-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006026495-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |