Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.42 |
| ▸ | HTR3B | O95264 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28788461 | 0.90 | HTR2C (0.51) | HTR2CHTR2AHTR2BTYRESR1 | |
| SCHEMBL5259883 | 0.82 | HTR2C (0.56) | HTR2CHTR2AHTR2BHTR1ACYP2C9 | |
| SCHEMBL30686491 | 0.82 | HTR2C (0.56) | HTR2CHTR2AHTR2BHTR1ACYP2C9 | |
| SCHEMBL28301106 | 0.80 | HTR2C (0.43) | HTR2CHTR2AHTR2BTYRESR1 | |
| SCHEMBL2804219 | 0.78 | CYP2A6 (0.55) | PDPK1 | |
| SCHEMBL1931747 | 0.78 | GPR84 (0.63) | HTR2AHTR1AHTR6 | |
| SCHEMBL5269899 | 0.78 | IMPDH2 (0.50) | HTR2CHTR2ACYP2C19TSHRHPGD | |
| SCHEMBL21623869 | 0.78 | HTR2A (0.56) | HTR2CHTR2AHTR2BHTR1DKDM4E | |
| SCHEMBL6498321 | 0.78 | HTR2C (0.51) | HTR2CHTR2AHTR2BTYRESR1 | |
| SCHEMBL2550995 | 0.78 | KDM4E (0.56) | HTR2CHTR2AHTR2BTYRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107513033-A | A kind of preparation method of 6 hydroxy indoxyl derivative | 湖南华腾制药有限公司 | 2017-12-26 | — | — | CN | claimed |
| EP-0271186-B1 | HYDROXYINDOLES AND THEIR USE IN DYEING | REPLIGEN CORPORATION (US) | 1992-12-30 | — | — | EP | claimed |
| CN-107513033-A | A kind of preparation method of 6 hydroxy indoxyl derivative | 湖南华腾制药有限公司 | 2017-12-26 | — | — | CN | disclosed |
| WO-2010009091-A2 | ANTI-INFLAMMATORY AND ANTI-ALLERGY EXTRACTS FROM NETTLE | HERBALSCIENCE GROUP, LLC (US) | 2010-01-21 | — | — | WO | disclosed |
| US-4208183-A | DISSOLVING IN AN ANHYDROUS HYDROXYLIC SOLVENT | L'OREAL (FR) | 1980-06-17 | — | — | US | disclosed |