Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.66 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273369 | 0.96 | VEGFA (0.72) | VEGFAEGLN1TSHRALDH1A1KDM4E | |
| SCHEMBL273696 | 0.88 | EGLN1 (0.85) | VEGFAEGLN1HRH3KDM4EHTT | |
| SCHEMBL271963 | 0.88 | EGLN1 (0.85) | VEGFAEGLN1HRH3KDM4EHTT | |
| SCHEMBL277668 | 0.88 | EGLN1 (0.85) | VEGFAEGLN1HRH3KDM4EHTT | |
| SCHEMBL273037 | 0.87 | EGLN1 (0.87) | VEGFAEGLN1ALDH1A1KDM4EHTT | |
| SCHEMBL272666 | 0.81 | VEGFA (0.81) | VEGFAEGLN1ALDH1A1KDM4EGAA | |
| SCHEMBL278202 | 0.81 | VEGFA (1.00) | VEGFAEGLN1ALDH1A1KDM4EHTT | |
| SCHEMBL5267745 | 0.79 | VEGFA (0.69) | VEGFAEGLN1HRH3TSHRALDH1A1 | |
| SCHEMBL272075 | 0.78 | VEGFA (0.70) | VEGFAEGLN1HRH3TSHRALDH1A1 | |
| SCHEMBL12598832 | 0.77 | VEGFA (0.73) | VEGFAEGLN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558579-B1 | N-ALKYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIALS | PROCTER & GAMBLE (US) | 2007-09-12 | — | — | EP | claimed |