Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269055 | 0.90 | TSHR (0.57) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5269241 | 0.89 | POLB (0.53) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5272917 | 0.89 | RAB9A (0.57) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5268351 | 0.88 | ALDH1A1 (0.53) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5266859 | 0.88 | POLB (0.52) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5269985 | 0.88 | MAPT (0.49) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5272599 | 0.87 | TSHR (0.51) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5267126 | 0.87 | ALDH1A1 (0.50) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5268204 | 0.86 | TSHR (0.47) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL5272580 | 0.85 | ALOX15 (0.49) | MAPTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |