SCHEMBL5272000

SCHEMBL5272000

CCCCCCCCCCCCCCCCc1cc2ccccc2c(C(=O)O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.56
MCL1 Q07820 6/20 0.56
BCL2L1 Q07817 5/20 0.56
BAK1 Q16611 5/20 0.56
KAT8 Q9H7Z6 3/20 0.56
PPARA Q07869 3/20 0.56
SAE1 Q9UBE0 2/20 0.56
PPARG P37231 2/20 0.56
EP300 Q09472 2/20 0.56
KAT5 Q92993 2/20 0.56
KAT2A Q92830 1/20 0.56
KAT2B Q92831 1/20 0.56
ME2 P23368 1/20 0.53
ME1 P48163 1/20 0.53
ME3 Q16798 1/20 0.53
F7 P08709 3/20 0.52
F3 P13726 3/20 0.52
MMP2 P08253 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HSD17B10 Q99714 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5270877 1.00 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5271656 1.00 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5272121 1.00 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5270254 1.00 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5271467 1.00 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL11434871 0.90 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5575880 0.90 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7184877 0.90 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5968378 0.88 MAPT (0.46) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL1176173 0.88 BID (0.51) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243609-B1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO (JP) 2007-10-24 EP disclosed
US-6906191-B2 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2005-06-14 US disclosed
US-20030018198-A1 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2003-01-23 US disclosed
EP-1243609-A1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2002-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018198-A1 Succinimide compounds and use thereof SRM, SMS, SGMS2 BID 1066/4885MCL1 4450/4885BCL2L1 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.