Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5562603 | 0.74 | SRC (0.42) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL527950 | 0.73 | KDM4E (0.43) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL1650792 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL30250019 | 0.67 | CYP3A4 (0.57) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL10638685 | 0.67 | ALDH1A1 (0.57) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL10635467 | 0.67 | CYP3A4 (0.57) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL2359770 | 0.67 | PDGFRB (0.41) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL13993586 | 0.67 | MPO (0.40) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL241448 | 0.67 | MPO (0.40) | ALDH1A1HSD17B10KDM4EHPGDMAPT | |
| SCHEMBL3783578 | 0.67 | EGFR (0.44) | ALDH1A1HSD17B10KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015901-A1 | METHODS FOR TREATING GASTRIC AND PANCREATIC MALIGNANCIES | GENZYME CORPORATION (US) | 2012-02-02 | — | — | WO | disclosed |