SCHEMBL5273247

SCHEMBL5273247

CC(Cl)(Cl)COP(=O)(OCC(C)(Cl)Cl)OCC(C)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 2/20 0.35
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29106448 0.79 LPAR3 (0.37)
SCHEMBL599835 0.77 TSHR (0.45) TSHRALDH1A1CYP3A4TP53TDP1
SCHEMBL5983546 0.77 ALDH1A1 (0.41) TSHRALDH1A1CYP3A4
SCHEMBL7045722 0.74 ALDH1A1 (0.40) TSHRALDH1A1CYP3A4
SCHEMBL7160257 0.70 TSHR (0.46) TSHRALDH1A1CYP3A4TP53TDP1
Phosphoric Acid SCHEMBL17477136 0.70 TSHR (0.39) TSHRALDH1A1CYP3A4TP53TDP1
SCHEMBL3686516 0.69 TSHR (0.38) TSHRALDH1A1CYP3A4
SCHEMBL7043593 0.69 TSHR (0.38) TSHRCYP3A4
SCHEMBL5908907 0.69 TSHR (0.65) TSHRCYP3A4TP53TDP1
SCHEMBL28861769 0.69 LMNA (0.33) TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524843-A Hydroxyl-terminated reactive flame retardant and preparation method thereof 青岛长荣化工科技有限公司 2022-05-24 CN disclosed
CN-114409697-A Double-end hydroxyl reaction type flame retardant and preparation method thereof 青岛长荣化工科技有限公司 2022-04-29 CN disclosed
EP-0544206-B1 Composition for thermosetting powder coating MITSUI CHEMICALS INC (JP) 2007-11-07 EP disclosed
US-5270391-A Acrylic copolymers with epoxy monomers, polycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1993-12-14 US disclosed
EP-0544206-A2 Composition for thermosetting powder coating MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-06-02 EP disclosed