SCHEMBL5273283

SCHEMBL5273283

CCCn1cnnc1CC(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280196 0.80 HSD11B1 (0.34) ADORA2AADORA2BADORA1
SCHEMBL5279872 0.79 ADORA2A (0.33) ADORA2AADORA2BADORA1
SCHEMBL5656633 0.77 ADORA2A (0.32) ADORA2AADORA2BADORA1
SCHEMBL3459979 0.77 ADORA2A (0.32) ADORA2AADORA2BADORA1
SCHEMBL5273469 0.76 CBLB (0.34)
SCHEMBL5279788 0.76 ALDH1A1 (0.35) ADORA2AADORA2BADORA1
Hydrochloric Acid SCHEMBL5655082 0.76 ADORA2A (0.31) ADORA2AADORA2BADORA1
SCHEMBL5284569 0.73 ADORA2A (0.32) ADORA2AADORA2BADORA1
SCHEMBL5656565 0.70 NPC1 (0.43) ADORA2AADORA2BADORA1
SCHEMBL5276026 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed