Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282060 | 0.77 | PKM (0.37) | PKMKDM4ECYP1A2CYP2C19GAA | |
| SCHEMBL5280176 | 0.77 | PKM (0.41) | PKMKDM4ECYP1A2CYP2C19GAA | |
| SCHEMBL5279006 | 0.76 | GRM2 (0.37) | KDM4ECYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL5275625 | 0.75 | KDM4E (0.48) | PKMKDM4ECYP1A2CYP2C19GAA | |
| SCHEMBL5279981 | 0.75 | PKM (0.36) | PKMKDM4ECYP1A2CYP2C19GAA | |
| SCHEMBL5274943 | 0.75 | CYP1A2 (0.34) | KDM4ECYP1A2CYP2C19GAAALDH1A1 | |
| SCHEMBL5276783 | 0.75 | MAPT (0.35) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL5276702 | 0.73 | PKM (0.35) | PKMKDM4ECYP1A2CYP2C19GAA | |
| SCHEMBL5282873 | 0.73 | GRM2 (0.40) | GAAALDH1A1MAPTHTTLMNA | |
| SCHEMBL5282629 | 0.72 | PKM (0.37) | PKMMAPTHTTPOLBCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |