Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282060 | 0.78 | PKM (0.37) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5278304 | 0.78 | ALDH1A1 (0.38) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5275625 | 0.77 | KDM4E (0.48) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5273686 | 0.77 | PKM (0.36) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5279981 | 0.77 | PKM (0.36) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5276702 | 0.75 | PKM (0.35) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5276496 | 0.75 | SMN1; SMN2 (0.38) | KDM4EALDH1A1ATML3MBTL1MAPT | |
| SCHEMBL5277811 | 0.75 | SMN1; SMN2 (0.38) | PKMCHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL5281132 | 0.74 | SMN1; SMN2 (0.36) | ALDH1A1ATML3MBTL1MAPTHTT | |
| SCHEMBL5280108 | 0.74 | CYP2C19 (0.32) | KDM4EALDH1A1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |