Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789073 | 0.87 | HTR7 (0.50) | HTR7HTR1ADRD2HTR2ADNM1 | |
| SCHEMBL19021680 | 0.86 | — | — | |
| SCHEMBL11938139 | 0.84 | HTR7 (0.48) | HTR7HTR1ADRD2HTR2ADNM1 | |
| SCHEMBL11938142 | 0.84 | HTR7 (0.48) | HTR7HTR1ADRD2HTR2ADNM1 | |
| SCHEMBL19592642 | 0.82 | — | — | |
| SCHEMBL15614034 | 0.82 | — | — | |
| SCHEMBL12039646 | 0.79 | — | — | |
| SCHEMBL18848499 | 0.78 | DNM1 (0.48) | HTR7HTR1ADRD2HTR2ADNM1 | |
| SCHEMBL11938143 | 0.77 | HTR7 (0.42) | HTR7HTR1ADRD2HTR2ADNM1 | |
| SCHEMBL9557517 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868594-A1 | GANGLIONIC BLOCKING AGENTS FOR THE TREATMENT OF EPITHELIAL DISEASES | Dow Pharmaceutical Sciences (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006104676-A1 | GANGLIONIC BLOCKING AGENTS FOR THE TREATMENT OF EPITHELIAL DISEASES | DOW PHARMACEUTICAL SCIENCES (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060216350-A1 | Ganglionic blocking agents for the treatment of epithelial diseases | DOW PHARMACEUTICAL SCIENCES | 2006-09-28 | — | — | US | disclosed |