SCHEMBL789073

SCHEMBL789073

CN(C)CCSCCN(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.50
HTR1A P08908 2/20 0.50
DRD2 P14416 2/20 0.50
HTR2A P28223 2/20 0.50
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
TSHR P16473 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
MAPT P10636 1/20 0.39
PRMT3 O60678 1/20 0.35
CARM1 Q86X55 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11938139 0.96 HTR7 (0.48) HTR7HTR1ADRD2HTR2AALDH1A1
SCHEMBL11938142 0.96 HTR7 (0.48) HTR7HTR1ADRD2HTR2AALDH1A1
SCHEMBL15614034 0.87
SCHEMBL5273733 0.87 HTR7 (0.42) HTR7HTR1ADRD2HTR2AALDH1A1
SCHEMBL11938143 0.87 HTR7 (0.42) HTR7HTR1ADRD2HTR2AALDH1A1
SCHEMBL5605130 0.85
SCHEMBL9557517 0.85
SCHEMBL6719978 0.85
SCHEMBL19021680 0.85
SCHEMBL12039646 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150306069-A1 METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS THE UNIVERSITY OF CHICAGO (US) 2015-10-29 US claimed
WO-2014085545-A1 METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS THE UNIVERSITY OF CHICAGO (US) 2014-06-05 WO claimed
US-3989671-A CHELATION, COPPER COMPOUNDS, IODINE COMPOUNDS, POLYMERIZATION CATALYSTS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-11-02 US claimed
EP-4400492-A1 ACRIDINE COMPOUND OSAKA UNIVERSITY (JP) 2024-07-17 EP disclosed
US-20240208999-A1 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-06-27 US disclosed
EP-4370507-A1 HYDROGENATED QUINOXALINES Otsuka Pharmaceutical Co., Ltd. (JP) 2024-05-22 EP disclosed
CN-117940408-A Acridine compounds 国立大学法人大阪大学 2024-04-26 CN disclosed
EP-4347597-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS Otsuka Pharmaceutical Co., Ltd. (JP) 2024-04-10 EP disclosed
US-20240109842-A1 ACRYLAMIDE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-04 US disclosed
US-11932657-B2 Heterocyclic compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-03-19 US disclosed
CN-117616013-A Hydrogenated quinoxalines 大塚制药株式会社 2024-02-27 CN disclosed
EP-1656983-A1 Process for deacidification of a gas with an absorbing solution in fractional regeneration Institut Français du Pétrole (FR) 2006-05-17 EP disclosed
EP-0915078-B1 Process for producing di-tert-butyl dicarbonate TOKUYAMA CORP (JP) 2001-05-02 EP disclosed
US-6020514-A Process for producing di-tert-butyl dicarbonate TOKUYAMA CORPORATION (JP) 2000-02-01 US disclosed
EP-0915078-A1 Process for producing di-tert-butyl dicarbonate TOKUYAMA CORPORATION (JP) 1999-05-12 EP disclosed
US-5294531-A BicycloUm.n.oealkane-1-ylcarbonylacetamide compound FUJI PHOTO FILM CO., LTD. (JP) 1994-03-15 US disclosed
US-5283166-A Yellow dye-forming coupler and silver halide color photographic light-sensitive material containing the same FUJI PHOTO FILM CO., LTD. (JP) 1994-02-01 US disclosed
US-4557754-A CHEMOTHERAPEUTIC ANTIMICROBIAL PREPARATION INSTITUT ORGANICHESKOI KHIMII (SU) 1985-12-10 US disclosed
US-4557754-A CHEMOTHERAPEUTIC ANTIMICROBIAL PREPARATION INSTITUT ORGANICHESKOI KHIMII (SU) 1985-12-10 US disclosed
US-4113488-A PHENOLIC COMPOUND AND SYNERGISTIC SULFIDE OR SULFOXIDE FUJI PHOTO FILM CO., LTD. (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306069-A1 METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS RAD51, MRE11, RAD50 HTR7 2543/4885HTR1A 2716/4885DRD2 4204/4885
US-20240109842-A1 ACRYLAMIDE COMPOUNDS HPGDS, MYADM, ACR HTR7 907/4885HTR1A 824/4885DRD2 4363/4885
US-11932657-B2 Heterocyclic compound AHR, PDGFRA, PDGFRB HTR7 154/4885HTR1A 126/4885DRD2 1049/4885
US-20240208999-A1 HETEROCYCLIC COMPOUND AHR, PDGFRA, PDGFRB HTR7 154/4885HTR1A 126/4885DRD2 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.