Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 4/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 6/20 | 0.46 |
| ▸ | ARG1 | P05089 | 4/20 | 0.46 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL1681675 | 1.00 | GGT1 (0.52) | GGT1SLC1A1PTGS1SLC7A11ARG2 | |
| Serine SCHEMBL6929773 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| Serine SCHEMBL2023740 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| Serine SCHEMBL4455818 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| (D)-Serine SCHEMBL43094 | 0.91 | — | — | |
| Serine SCHEMBL1332181 | 0.91 | — | — | |
| Serine SCHEMBL2023739 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| Serine SCHEMBL6929758 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| Serine SCHEMBL6520918 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR | |
| (D)-Serine SCHEMBL6038168 | 0.91 | SLC1A1 (0.59) | GGT1SLC1A1PTGS1SLC7A11GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715646-B2 | Methods of determining need for anti-coagulation therapy | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130209435-A1 | METHODS FOR PREDICTING RISK OF STROKE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2598881-A2 | METHODS FOR PREDICTING RISK OF STROKE | The Board of Trustees of the University of Illinois (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016150-A2 | METHODS FOR PREDICTING RISK OF STROKE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-02 | — | — | WO | disclosed |
| US-5332755-A | Leukotriene antagonists as antiinflammatory agents and antiallergens | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| US-5221760-A | Intermediates, leukotriene antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| US-5159097-A | An arylphosphorous compound as chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
| US-5118700-A | Leukotriene antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| EP-0341551-B1 | ALKENOIC ACID DERIVATIVES | BAYER AG (DE) | 1992-04-01 | — | — | EP | disclosed |
| US-5041638-A | Leucotriene antagonist; treatment of respiratory system disorders, cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0341551-A1 | Alkenoic acid derivatives | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |