Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265107 | 0.81 | CHEK1 (0.44) | LMNACHEK1AURKADAPK3JAK2 | |
| SCHEMBL10368739 | 0.69 | HSD11B1 (0.45) | LMNAALDH1A1HSD17B10L3MBTL1GAA | |
| SCHEMBL28415395 | 0.69 | SLC6A2 (0.48) | LMNACHEK1AURKADAPK3JAK2 | |
| Bromide SCHEMBL28412457 | 0.68 | SLC6A2 (0.47) | LMNACHEK1AURKADAPK3JAK2 | |
| SCHEMBL926329 | 0.67 | L3MBTL1 (0.67) | LMNAALDH1A1TDP1ADRA2BPTGS1 | |
| SCHEMBL6904077 | 0.65 | CHEK1 (0.65) | LMNACHEK1AURKADAPK3JAK2 | |
| SCHEMBL5272690 | 0.65 | CHEK1 (0.64) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL18639529 | 0.65 | SNCA (0.40) | LMNACHEK1AURKADAPK3JAK2 | |
| SCHEMBL17187194 | 0.65 | HDAC4 (0.48) | CHEK1AURKADAPK3JAK2PRKD3 | |
| Iodide SCHEMBL28598560 | 0.64 | CHEK1 (0.62) | LMNACHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587793-B1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX SA (FR) | 2007-11-28 | — | — | EP | disclosed |