SCHEMBL6904077

SCHEMBL6904077

CN1c2ccccc2C(c2ccccc2)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.65
AURKA O14965 1/20 0.65
DAPK3 O43293 1/20 0.65
JAK2 O60674 1/20 0.65
PRKD3 O94806 1/20 0.65
MAP4K4 O95819 1/20 0.65
PAK4 O96013 1/20 0.65
ABL1 P00519 1/20 0.65
NTRK1 P04629 1/20 0.65
LCK P06239 1/20 0.65
FYN P06241 1/20 0.65
CSF1R P07333 1/20 0.65
RET P07949 1/20 0.65
IGF1R P08069 1/20 0.65
MET P08581 1/20 0.65
PDGFRB P09619 1/20 0.65
PIM1 P11309 1/20 0.65
FGFR1 P11362 1/20 0.65
PDGFRA P16234 1/20 0.65
PRKACA P17612 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL28598560 0.98 CHEK1 (0.62) CHEK1AURKADAPK3JAK2PRKD3
Iodide SCHEMBL29628899 0.98 CHEK1 (0.62) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL28458018 0.92 CHEK1 (0.57) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL22480499 0.88 CHEK1 (0.53) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL14154058 0.86 CHEK1 (0.50) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL5272690 0.86 CHEK1 (0.64) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL22402101 0.85 CHEK1 (0.62) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL9952138 0.84 CHEK1 (0.49) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL29915854 0.84 CHEK1 (0.49) CHEK1AURKADAPK3JAK2PRKD3
SCHEMBL3423462 0.81 PDGFRB (0.57) CHEK1AURKADAPK3JAK2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129029-A1 ACRIDINE COMPOUND OSAKA UNIVERSITY (JP) 2025-04-24 US disclosed
EP-4400492-A1 ACRIDINE COMPOUND OSAKA UNIVERSITY (JP) 2024-07-17 EP disclosed
CN-117940408-A Acridine compounds 国立大学法人大阪大学 2024-04-26 CN disclosed
WO-2023033165-A1 ACRIDINE COMPOUND 国立大学法人大阪大学 2023-03-09 WO disclosed
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER UNIV NEW YORK (US) 2022-10-13 US disclosed
CN-110699677-B Self-assembled film of methylacridine salt on carbon steel surface and corrosion resistance 威海海洋生物医药产业技术研究院有限公司 2022-07-15 CN disclosed
US-20220144862-A1 ORGANIC COMPOUND AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2022-05-12 US disclosed
US-20200308129-A1 SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-01 US disclosed
US-20200212301-A1 SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-02 US disclosed
WO-2020070672-A1 HYDRIDE DONORS AS AN ADDITIVE FOR REDUCING LOW SPEED PRE-IGNITION EVENTS CHEVRON ORONITE COMPANY LLC (US) 2020-04-09 WO disclosed
CN-110699677-A Self-assembled film and corrosion resistance of methylacridine salt on carbon steel surface 哈尔滨工业大学(威海) 2020-01-17 CN disclosed
CN-108658885-A A kind of synthetic method of 2,4 diaryl oxazole 沅江华龙催化科技有限公司 2018-10-16 CN disclosed
CN-108440438-A A method of 2,4 diaryl oxazoles are built jointly by acetophenone compounds and ammonium persulfate and dimethyl sulfoxide (DMSO) 沅江华龙催化科技有限公司 2018-08-24 CN disclosed
CN-108383803-A A kind of synthetic method of 2,4 2 substituted oxazoline 沅江华龙催化科技有限公司 2018-08-10 CN disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed
EP-1424126-A1 PHOTOOXIDATION CATALYSTS AND PROCESS FOR PREPARATION OF ALDEHYDES Showa Denko K.K. (JP) 2004-06-02 EP disclosed
US-6720458-B2 HALOGENATED AROMATIC NITRILE SHOWA DENKO K.K. (JP) 2004-04-13 US disclosed
US-20030098229-A1 Photooxidation catalyst and production process for aldehyde derivatives SHOWA DENKO K.K. 2003-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030098229-A1 Photooxidation catalyst and production process for aldehyde derivatives AOX1, PPOX, NOX4 CHEK1 3147/4885AURKA 3634/4885DAPK3 4564/4885
US-20220144862-A1 ORGANIC COMPOUND AND APPLICATION THEREOF TEAD2, TEAD1, TEAD4 CHEK1 2174/4885AURKA 1785/4885DAPK3 3108/4885
US-20200212301-A1 SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES SELE, KCNB2, SCNN1B CHEK1 3844/4885AURKA 2935/4885DAPK3 2686/4885
US-20250129029-A1 ACRIDINE COMPOUND ACR, XDH, DRD4 CHEK1 1538/4885AURKA 1741/4885DAPK3 2618/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 CHEK1 1527/4885AURKA 459/4885DAPK3 1553/4885
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER ALG1, PPOX, MANBA CHEK1 1589/4885AURKA 3677/4885DAPK3 2052/4885
US-20200308129-A1 SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES DDC, CHRM5, AFF2 CHEK1 3260/4885AURKA 315/4885DAPK3 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.