Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 18/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552606 | 0.82 | MMP3 (0.57) | — | |
| SCHEMBL13781563 | 0.81 | HCAR2 (0.52) | HCAR2LTB4RPOLB | |
| SCHEMBL3561642 | 0.80 | SLC12A2 (0.41) | HCAR2POLB | |
| SCHEMBL3561743 | 0.80 | NPC1 (0.55) | HCAR2POLB | |
| SCHEMBL13781560 | 0.78 | ALDH1A1 (0.56) | HCAR2LTB4RPOLB | |
| SCHEMBL12756640 | 0.77 | HCAR2 (0.59) | HCAR2 | |
| SCHEMBL1490241 | 0.76 | ALOX15 (0.53) | HCAR2 | |
| SCHEMBL1490744 | 0.76 | HDAC2 (0.47) | HCAR2POLB | |
| SCHEMBL1490571 | 0.76 | HCAR2 (0.59) | HCAR2POLB | |
| SCHEMBL5062205 | 0.76 | HCAR2 (0.64) | HCAR2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853579-A2 | 2-SUBSTITUTED 5-MEMBERED HETEROARYL CARBOXYLATES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006085113-A2 | 2-SUBSTITUTED 5-MEMBERED HETEROARYL CARBOXYLATES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-17 | — | — | WO | disclosed |