Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050377 | 1.00 | PTGS2 (0.56) | PTGS2CNR1CNR2AKR1B1TNKS2 | |
| SCHEMBL23266717 | 0.98 | PTGS2 (0.58) | PTGS2CNR1CNR2AKR1B1TNKS2 | |
| SCHEMBL224550 | 0.92 | TNKS2 (0.56) | PTGS2CNR1CNR2AKR1B1TNKS2 | |
| SCHEMBL10296730 | 0.89 | PTGS2 (0.50) | PTGS2CNR1CNR2AKR1B1TNKS2 | |
| SCHEMBL919408 | 0.83 | AKR1B1 (0.55) | PTGS2AKR1B1TNKS2CYP19A1CALM1 | |
| SCHEMBL15746740 | 0.82 | HDAC1 (0.62) | CYP4F2CYP4A11HDAC1HDAC6 | |
| SCHEMBL17274721 | 0.82 | HDAC1 (0.62) | CYP4F2CYP4A11HDAC1HDAC6 | |
| SCHEMBL18586439 | 0.82 | PTGS2 (0.73) | PTGS2CNR1CNR2CYP19A1ALDH1A1 | |
| SCHEMBL31185832 | 0.82 | PTGS2 (0.73) | PTGS2CNR1CNR2CYP19A1ALDH1A1 | |
| SCHEMBL31185803 | 0.82 | PTGS2 (0.73) | PTGS2CNR1CNR2CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005122670-A2 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL INDÚSTRIA QUÍMICA LTDA. (BR) | 2005-12-29 | — | — | WO | claimed |
| WO-2005122670-A3 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL IND QUIMICA LTDA (BR) | 2007-07-05 | — | — | WO | disclosed |
| WO-2005122670-A2 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL INDÚSTRIA QUÍMICA LTDA. (BR) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005122670-A2 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL INDÚSTRIA QUÍMICA LTDA. (BR) | 2005-12-29 | — | — | WO | disclosed |