Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275704 | 0.89 | PTGS2 (0.56) | PTGS2TNKS2CNR1CNR2CALM1 | |
| SCHEMBL1050377 | 0.89 | PTGS2 (0.56) | PTGS2TNKS2CNR1CNR2CALM1 | |
| SCHEMBL23266717 | 0.87 | PTGS2 (0.58) | PTGS2TNKS2CNR1CNR2CALM1 | |
| SCHEMBL11766486 | 0.85 | CALM1 (0.44) | PTGS2TNKS2CALM1AKR1B1CYP19A1 | |
| SCHEMBL8229999 | 0.84 | PTGS2 (0.65) | PTGS2CNR1CNR2CYP3A4 | |
| SCHEMBL29530874 | 0.81 | CA2 (0.43) | PTGS2TNKS2CNR1CNR2CYP4F2 | |
| SCHEMBL224550 | 0.81 | TNKS2 (0.56) | PTGS2TNKS2CNR1CNR2CALM1 | |
| SCHEMBL28266224 | 0.81 | TNKS2 (0.41) | PTGS2TNKS2CNR1CNR2CYP4F2 | |
| SCHEMBL15787170 | 0.81 | PTGS2 (0.47) | PTGS2CALM1AKR1B1CYP19A1TACR1 | |
| SCHEMBL13618169 | 0.79 | PTGS2 (0.68) | PTGS2CALM1AKR1B1CYP19A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172339-A1 | ANGIOGENIC RESORCINOL DERIVATIVES | NORTHEASTERN UNIVERSITY (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172339-A1 | ANGIOGENIC RESORCINOL DERIVATIVES | CNR1, CNR2, KDR | PTGS2 587/4885TNKS2 3056/4885CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.